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DNA Damage Response and Oxidative Stress in the Resistance of Multiple Myeloma Cells to Genotoxic Treatment

2025-09-10

Abstract excerpt

The DNA Damage Response (DDR) network is an essential machinery for maintaining genomic integrity, with DDR defects being implicated in cancer initiation, progression and treatment resistance. Moreover, oxidative stress, an imbalance between reactive oxygen species production and antioxidant defence, can significantly impact cell viability, leading to cell death or survival. Herein, we tested the hypothesis that D...

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Literature Corpus work
52b2aec0-5842-5b8b-96a7-ff19b7d8862d
DOI
10.20944/preprints202509.0870.v1
Open publication

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DNA Damage Response and Oxidative Stress in the Resistance of Multiple Myeloma Cells to Genotoxic TreatmentDOI 10.20944/preprints202509.0870.v1
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