Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma

18 Sept 2019

Abstract excerpt

Multiple myeloma (MM) is a malignancy characterized by accumulation of malignant plasma cells within the bone marrow (BM). MM is considered mostly without definitive treatment because of the inability of standard of care therapies to overcome drug-resistant relapse. Genotoxic agents are used in the treatment of MM and exploit the fact that DNA double-strand breaks are highly cytotoxic for cancer cells. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Multiple Myeloma Research and Treatments
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31620167
DOI: 10.3389/fgene.2019.00861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple MyelomaPMID 31620167Read ↗

Understanding DNA Damage Response and DNA Repair in Multiple MyelomaSemantic proximity Read ↗

DNA Damage Response and Oxidative Stress in the Resistance of Multiple Myeloma Cells to Genotoxic TreatmentSemantic proximity Read ↗

Myeloma and DNA damageSemantic proximity Read ↗

DNA repair pathways in human multiple myelomaSemantic proximity Read ↗

DNA Damage Response in Multiple Myeloma: The Role of the Tumor MicroenvironmentSemantic proximity Read ↗

The Interplay between the DNA Damage Response (DDR) Network and the Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Multiple MyelomaSemantic proximity Read ↗

Genomic instability in multiple myeloma: mechanisms and therapeutic implicationsSemantic proximity Read ↗

The Role of Epigenetics in the Development and Progression of Multiple MyelomaSemantic proximity Read ↗

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategySemantic proximity Read ↗

Molecular mechanisms in multiple myeloma drug resistance.Semantic proximity Read ↗

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.Semantic proximity Read ↗

Multiple Myeloma: Challenges Encountered and Future Options for Better Treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.