Article

Bone marrow derived extracellular vesicles activate osteoclast differentiation in traumatic brain injury induced bone loss

2018-10-23

Abstract excerpt

Traumatic brain injury (TBI) is a major source of worldwide morbidity and mortality. Patients suffering from TBI exhibit a higher susceptibility to bone loss and an increased rate of bone fractures; however, the underlying mechanisms remain poorly defined. Herein, we observed significantly lower bone quality and elevated levels of inflammation in bone and bone marrow niche after controlled cortical impact-induced...

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Literature Corpus work: 52ae8c84-2491-55b3-92dd-9181de4b911e
DOI: 10.20944/preprints201810.0529.v1

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