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Article

Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma

21 Aug 2019

Abstract excerpt

Polytraumatic injuries, specifically long bone fracture and traumatic brain injury (TBI), frequently occur together. Clinical observation has long held that TBI can accelerate fracture healing, yet the complexity and heterogeneity of these injuries has produced conflicting data with limited information on underlying mechanisms. We developed a murine polytrauma model with TBI and fracture to evaluate healing in a...

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PMID: 31434912
DOI: 10.1038/s41598-019-48126-z

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