Article

Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury

2022-04-05

Abstract excerpt

<h4>Background</h4> Traumatic Brain Injury (TBI) is characterized by massive changes in neuronal excitation, from acute excitotoxicity to chronic hyper- or hypoexcitability. Nuclear calcium signaling pathways are involved in translating changes in synaptic inputs and neuronal activity into discrete transcriptional programs which not only affect neuronal survival and synaptic integrity, but also the crosstalk betw...

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Literature Corpus work: 5487604b-f044-586a-8cc7-dbcf467e066f
DOI: 10.1101/2022.04.03.486874

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