Article

FibrilPaint: a class of amyloid-targeting peptides

2024-08-25

Abstract excerpt

Amyloid fibrils are a common pathological hallmark in multiple neurodegenerative diseases, yet molecular tools to selectively recognise and manipulate them remain scarce. We report FibrilPaints, a family of modular peptides designed for selective amyloid binding and adaptable chemical functionality. The degenerative amyloid-targeting unit of FibrilPaints, W 5 P 4 H 3 R 2 , has a high content of π-stacking and...

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Literature Corpus work: 52a17ba4-b9ef-5d4c-b9e0-390615433f5f
DOI: 10.1101/2024.08.25.609586

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