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Article

A KLVFFAE-Derived Peptide Probe for Detection of Alpha-Synuclein Fibrils.

Applied biochemistry and biotechnology - 1 Apr 2020

Wood Amy, Chau Edward, Yang Yanxi, Kim Jin Ryoun

Abstract excerpt

Aggregation of an amyloid protein, α-synuclein (αS), is a critical step in the neurodegenerative pathway of Parkinson's diseases (PD). Specific detection of amyloid conformers (i.e., monomers, oligomers, and fibrils) produced during αS aggregation is critical in better understanding a molecular basis of PD and developing a diagnostic tool. While various molecular probes are available for detection of αS fibrils,...

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Identifiers

PMID: 31776941
DOI: 10.1007/s12010-019-03197-6
PMCID: PMC7289322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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