Article

Shiftless, A Critical Piece of the Innate Immune Response to Viral Infection

2022-05-09

Abstract excerpt

Since its initial characterization in 2016, the interferon stimulated gene Shiftless (SHFL) has proven to be a critical piece of the innate immune response to viral infection. SHFL expression stringently restricts the replication of multiple DNA, RNA, and retroviruses with an extraordinary diversity of mechanisms that differ from one virus to the next. These inhibitory strategies include the negative regulation of...

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Literature Corpus work: 5291ce4f-06e3-512a-8dd7-9325ff6427c9
DOI: 10.20944/preprints202205.0104.v1

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