Article

NLRP3 Inflammasome, NEK7 and Major Depressive Disorder

2022-07-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Association between inflammation and depression has been known for a long time. Activation of pro-inflammatory molecular complexes such as inflammasomes in depression was suggested as the most relevant hypothesis among many others. Psychological stress is considered to cause sterile inflammation through inflammasomes, and the NLRP3 inflammasome was proposed as a crucial molecu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5280baf9-88de-5d61-861c-8e7f2ea5824b
DOI: 10.1101/2022.07.16.22277717

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NLRP3 Inflammasome, NEK7 and Major Depressive DisorderDOI 10.1101/2022.07.16.22277717Read

Suppression of NLRP3 inflammasome attenuates stress-induced depression-like behavior in NLGN3-deficient mice.Semantic proximity Read

Proinflammatory Cytokines: A Common Denominator in Depression and Somatic Symptoms?Semantic proximity Read

Investigating Inflammation in depression in the chronically ill: A theoretical modelSemantic proximity Read

From Immune Activation to Cell Death: Investigating the Pro-inflammatory Phenotype of PBMCs in Major Depressive DisorderSemantic proximity Read

Inflammation and depression.Semantic proximity Read

Complex Neurobiological Mechanisms and Risk Factors Underlying Late-Life Depression.Semantic proximity Read

Proinflammatory phenotype in major depressive disorder with adulthood adversity: In line with social signal transduction theory of depression.Semantic proximity Read

Comprehensive analysis of endoplasmic reticulum stress and immune infiltration in major depressive disorderSemantic proximity Read

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.Semantic proximity Read

Major depressive disorder, neuroticism, suicidal behaviors, and depression severity are all associated with neurotoxic immune networks and their intricate interactions with metabolic syndromeSemantic proximity Read

The NLRP3 Inflammasome in Stress Response: Another Target for the Promiscuous CannabidiolSemantic proximity Read

Emerging Roles of Inflammasomes in Cardiovascular DiseasesSemantic proximity Read