Article

Quantification of lactoyl-CoA by liquid chromatography mass spectrometry in mammalian cells and tissues

2020-03-17

Abstract excerpt

Lysine lactoylation is a recently described protein post-translational modification (PTM). However, the biochemical pathways responsible for this acylation remain unclear. Two metabolite-dependent mechanisms have been proposed: enzymatic histone lysine lactoylation derived from lactoyl-coenzyme A (lactoyl-CoA, also termed lactyl-CoA), and non-enzymatic lysine lactoylation resulting from acyl-transfer via lactoyl-g...

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Literature Corpus work: 525cab5a-ed68-593a-a713-c4922b1391cb
DOI: 10.1101/2020.03.15.992859

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