Article
Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2009
Paterson Andrew D, Lopes-Virella Maria F, Waggott Daryl, Boright Andrew P, Hosseini S Mohsen, Carter Rickey E, Shen Enqing, Mirea Lucia, Bharaj Bhupinder, Sun Lei, Bull Shelley B
Abstract excerpt
BACKGROUND: Elevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype. METHODS AND RESULT...
Topics
- ABO Blood-Group System
- Alleles
- Diabetes Mellitus, Type 1
- E-Selectin
- Female
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- Humans
- Male
- Multivariate Analysis
- Polymorphism, Single Nucleotide
- Reference Values