Article
Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2009
Paterson Andrew D, Lopes-Virella Maria F, Waggott Daryl, Boright Andrew P, Hosseini S Mohsen, Carter Rickey E, Shen Enqing, Mirea Lucia, Bharaj Bhupinder, Sun Lei, Bull Shelley B
Abstract excerpt
BACKGROUND: Elevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype. METHODS AND RESULTS: We performed a high-resolution genome-wide association study of serum soluble E-selectin levels in 685 white...
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