Article
ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis.
Atherosclerosis - 1 Aug 2016
Larson Nicholas B, Bell Elizabeth J, Decker Paul A, Pike Mindy, Wassel Christina L, Tsai Michael Y, Pankow James S, Tang Weihong, Hanson Naomi Q, Alexander Kristine, Zakai Neil A, Cushman Mary, Bielinski Suzette J
Abstract excerpt
BACKGROUND AND AIMS: ABO blood type is associated with cardiovascular disease, although the underlying mechanisms are presumed to be complex. While the relationship between non-O blood types and von Willebrand Factor (vWF) is well-established, associations with cellular adhesion molecules (CAMs) across diverse populations are understudied. METHODS: We genetically inferred ABO alleles for N = 6202 participants...
Topics
- ABO Blood-Group System
- Aged
- Aged, 80 and over
- Alleles
- Atherosclerosis
- Cell Adhesion
- E-Selectin
- Endothelium, Vascular
- Ethnicity
- Female