Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.

doi:10.1161/CIRCGENETICS.111.960682

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Article

Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.

Circulation. Cardiovascular genetics - 1 Dec 2011

Kiechl Stefan, Paré Guillaume, Barbalic Maja, Qi Lu, Dupuis Josée, Dehghan Abbas, Bis Joshua C, Laxton Ross C, Xiao Qingzhong, Bonora Enzo, Willeit Johann, Xu Qingbo, Witteman Jacqueline C M, Chasman Daniel, Tracy Russell P, Ballantyne Christie M, Ridker Paul M, Benjamin Emelia J, Ye Shu

Abstract excerpt

BACKGROUND: Circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin have been associated with variation at the ABO locus. To evaluate these associations and the effect sizes, we performed a meta-analysis with new and previous reported data for polymorphism rs579459. METHODS AND RESULTS: Compared with major allele homozygotes, heterozygotes and minor allele...

Topics

ABO Blood-Group System
Adult
Aged
Aged, 80 and over
Cohort Studies
E-Selectin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genetic Variation

Humans

Intercellular Adhesion Molecule-1

Male

Middle Aged

P-Selectin

Polymorphism, Single Nucleotide

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Identifiers

PMID: 22010135
DOI: 10.1161/CIRCGENETICS.111.960682
PMCID: PMC3278232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22010135-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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