Back to search

Article

Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in <i>Cryptococcus neoformans</i>

2020-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Qsp1 is a secreted quorum sensing peptide required for virulence of the fungal meningitis pathogen Cryptococcus neoformans. Qsp1 functions to control cell wall integrity in vegetatively growing cells and also functions in mating. Rather than acting on a cell surface receptor, Qsp1 is imported to act intracellularly via the predicted oligopeptide transporter Opt1. Here, we identify a transcripti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e6689f95-37e6-54ff-bc8f-23251b9c3cf3
DOI
10.1101/2020.03.30.016329
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in <i>Cryptococcus neoformans</i>DOI 10.1101/2020.03.30.016329
Intracellular Action of a Secreted Peptide Required for Fungal Virulence.Semantic proximity
The transcription factor Pdr802 regulates Titan cell formation, quorum sensing, and pathogenicity of <i>Cryptococcus neoformans</i>Semantic proximity
Transcription Factors and Intracellular Proteins Orchestrate Phenotypic Adaptation in Cryptococcus neoformans for Survival and Human InfectionsSemantic proximity
Transcriptional Profiling of Patient Isolates Identifies a Novel TOR Regulatory Pathway in Cryptococcal VirulenceSemantic proximity
Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host ResponseSemantic proximity
SpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A StreptococcusSemantic proximity
Leveraging a new data resource to define the response of <i>C. neoformans</i> to environmental signalsSemantic proximity
Suppressed macrophage response to quorum-sensing-active <i>Streptococcus pyogenes</i> occurs at the level of the nucleusSemantic proximity
A trade-off between proliferation and defense in the fungal pathogen <i>Cryptococcus</i> at alkaline pH is controlled by the transcription factor GAT201Semantic proximity
Alternative TSS use is widespread in <i>Cryptococcus</i> fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1Semantic proximity
A broadly distributed new class of quorum sensing signals mediate bacterial intercellular signalingSemantic proximity
The interactome of <i>Cryptococcus neoformans</i> Rmt5 reveals multiple regulatory points in fungal cell biology and pathogenesisSemantic proximity
Select a neighboring publication to make it the new centre.