Article

EnhancerDetector: Enhancer Discovery from Human to Fly via Interpretable Deep Learning

2025-05-31

Abstract excerpt

<h4>Background: </h4> Deciphering how enhancers encode regulatory information in DNA remains a central genomics challenge, as sequencing outpaces functional annotation. A key question is whether enhancers possess an intrinsic, sequence-based "enhancerness" distinguishing them from other regions, independent of species, cell type, or assay. Confirming its existence and learnability is both biologically fundamental...

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Literature Corpus work: f7330e70-f045-5e8b-886a-ce018752c877
DOI: 10.1101/2025.05.28.656532

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