Article

Contribution of Circulating Mfge8 to Human T2DM and Cardiovascular Disease

2024-02-07

Abstract excerpt

MFGE8 is a major exosome (EV) protein known to mediate inflammation and atherosclerosis in type 2 diabetes mellitus (T2DM) in animal studies. However, its role in the pathophysiology of human T2DM, obesity, and cardiovascular disease has been controversial and less explored. Earlier, we reported a rare Asian Indian population-specific missense variant (rs371227978; Arg148His) in the MFGE8 associated with increased...

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Literature Corpus work: 516e9379-fe1c-5486-b06a-55a6431791bc
DOI: 10.20944/preprints202402.0454.v1

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