Article

Induced pluripotent stem cell derived liver model for the study of PNPLA3-associated non-alcoholic fatty liver disease

2020-01-01

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease in the developed world, afflicting approximately one in four adults globally. NAFLD is defined by the accumulation of fat within the liver which ranges in severity from simple steatosis to non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma. Until recently, NAFLD has been considered to be a consequ...

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Literature Corpus work: 514bdad2-df38-5495-b161-b03c0ec8a79b
DOI: 10.17863/cam.63096

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