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Concise Review: Current Status and Future Directions on Research Related to Nonalcoholic Fatty Liver Disease

4 Jul 2016

Abstract excerpt

Considered a feature of the metabolic syndrome, nonalcoholic fatty liver disease (NAFLD), is associated with insulin resistance, type 2 diabetes, obesity and drug toxicity. Its prevalence is estimated at about 30% in western countries mainly due to sedentary life styles and high fat diets. Genome-wide association studies have identified polymorphisms in several genes, for example, PNPLA3, and TM6SF2 which confer...

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PMID: 27374784
DOI: 10.1002/stem.2454

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