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Standard Issue: Copy number heterogeneity of JC virus standards discovered through next-generation sequencing

2016-11-03

Abstract excerpt

Quantitative PCR is a diagnostic mainstay of clinical virology, and accurate quantitation of viral load among labs requires the use of international standards. However, the use of multiple passages of viral isolates to obtain sufficient material for international standards may result in genomic changes that complicate their use as quantitative standards. We performed next-generation sequencing to gain single-nucle...

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Literature Corpus work: 51477720-a5c4-55c4-a76d-ae7fb09e9603
DOI: 10.1101/085415

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