Article

Human Cytomegalovirus Genomes Sequenced Directly from Clinical Material: Variation, Multiple-Strain Infection, Recombination and Mutation

2018-12-23

Abstract excerpt

<h4>ABSTRACT</h4> The genomic characteristics of human cytomegalovirus (HCMV) strains sequenced directly from clinical pathology samples were investigated, focusing on variation, multiple-strain infection, recombination and natural mutation. A total of 207 datasets generated in this and previous studies using target enrichment and high-throughput sequencing were analysed, in the process facilitating the determina...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 54b14443-97b1-582d-8d21-c33d20326032
DOI: 10.1101/505735

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human Cytomegalovirus Genomes Sequenced Directly from Clinical Material: Variation, Multiple-Strain Infection, Recombination and MutationDOI 10.1101/505735Read

Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene LossSemantic proximity Read

High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive RecombinationSemantic proximity Read

Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombinationSemantic proximity Read

Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challengesSemantic proximity Read

Characterization of Human Cytomegalovirus Genome Diversity in Immunocompromised Hosts by Whole-Genome Sequencing Directly From Clinical Specimens.Semantic proximity Read

Human cytomegalovirus multiple-strain infections and viral population diversity in haematopoietic stem cell transplant recipients analysed by high-throughput sequencing.Semantic proximity Read

Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomesSemantic proximity Read

Drivers of within-host genetic diversity in acute infections of viruses.Semantic proximity Read

Cytomegalovirus Genetic Diversity and Evolution: Insights into Genotypes and Their Role in Viral PathogenesisSemantic proximity Read

A method enabling high-throughput sequencing of human cytomegalovirus complete genomes from clinical isolates.Semantic proximity Read

Genomic and Functional Characteristics of Human Cytomegalovirus Revealed by Next-Generation SequencingSemantic proximity Read

Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients.Semantic proximity Read