Article
Rapid genome assembly and comparison decode intrastrain variation in human alphaherpesviruses.
mBio - 31 Mar 2015
Parsons Lance R, Tafuri Yolanda R, Shreve Jacob T, Bowen Christopher D, Shipley Mackenzie M, Enquist L W, Szpara Moriah L
Abstract excerpt
UNLABELLED: Herpes simplex virus (HSV) is a widespread pathogen that causes epithelial lesions with recurrent disease that manifests over a lifetime. The lifelong aspect of infection results from latent viral infection of neurons, a reservoir from which the virus reactivates periodically. Recent work has demonstrated the breadth of genetic variation in globally distributed HSV strains. However, the amount of...
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