Article

KDM6B Inhibition Enhances Chemotherapeutic Response in Small Cell Lung Cancer via Epigenetic Regulation of Apoptosis and Ferroptosis

2025-08-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid progression and the frequent emergence of resistance to standard chemotherapeutic agents such as cisplatin (DDP) and etoposide (VP16), resulting in poor clinical outcomes. <bold>Methods and Results:</bold> To elucidate mechanisms underlying chemoresistance, we conducted a...

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Literature Corpus work: 513d11c9-99b0-5661-9348-7958d5c62a43
DOI: 10.21203/rs.3.rs-7016767/v1

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