Article

Integrative pharmacogenomic profiling identifies novel cancer drugs and gene networks modulating ferroptosis sensitivity in pan-cancer

2020-06-11

Abstract excerpt

<h4>Background: </h4> Ferroptosis is an apoptosis-independent cell death program implicated in various diseases including cancer. Emerging evidence has demonstrated the promise of pharmacological induction of ferroptosis as a novel anti-cancer approach, but the molecular underpinnings of ferroptosis regulation and biomarkers associated with sensitivity to ferroptosis indcuers has been poorly defined. <h4>Methods:<...

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Literature Corpus work: 9147619c-bd22-52b4-9674-2bcaed224e80
DOI: 10.21203/rs.3.rs-34574/v1

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