Article

Break-up and Recovery of Harmony between Direct and Indirect Pathways in The Basal Ganglia; Huntington's Disease and Treatment

2023-10-20

Abstract excerpt

The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and emotion. Such BG functions could be made via competitive harmony between the two competing pathways, direct pathway (DP) (facilitating movement) and indirect pathway (IP) (suppressing movement). As a result of break-up of harmony between DP and IP, there appear pathological states with disorder for movement, cognition, and psyc...

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Literature Corpus work: 513044e3-d5e8-5853-9f38-f0978ce1546f
DOI: 10.1101/2023.10.17.562800

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