Article

The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

2020-04-10

Abstract excerpt

<h4>ABSTRACT</h4> The host defence peptide cathelicidin (LL-37 in humans, mCRAMP in mice) is released from neutrophils by de-granulation, NETosis and necrotic cell death; it has potent antibacterial, antiviral and antifungal activity as well as being a powerful immunomodulator. It is released in proximity to CD4 + T cells during inflammatory and infectious disease but its impact on T cell phenotype is scarcely u...

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Literature Corpus work: 5123dae9-4440-54b1-896d-07706612099d
DOI: 10.1101/2020.04.10.035543

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