Article

Islet Gene View - a tool to facilitate islet research

2018-10-05

Abstract excerpt

Changes in the hormone-producing pancreatic islets are central culprits in type 2 diabetes (T2D) pathogenesis. Characterization of gene expression in islets how it is altered in T2D are therefore vital in understanding islet function and T2D pathogenesis. We leveraged RNA-sequencing and genome-wide genotyping in islets from 188 donors to create the Islet Gene View (IGW) platform to make this information easily acc...

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Literature Corpus work: 511804dd-5239-574b-84d4-7d6f6257786c
DOI: 10.1101/435743

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