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Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis

2023-01-24

Abstract excerpt

<h4>Background: </h4> Reactive oxygen species (ROS) overproduction and excessive hypoxia play pivotal roles in the initiation and progression of ulcerative colitis (UC). Synergistic ROS scavenging and generating O 2 could be a promising strategy for UC treatment. Methods Ceria nanozymes (CNPs) are fabricated using a modified reverse micelle method. We investigate hypoxia attenuating and ROS scavenging of CNPs in...

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Literature Corpus work
5110d3d9-f2b4-5913-8e6c-98c94a55ae79
DOI
10.21203/rs.3.rs-2457999/v1
Open publication

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