Efficient active hydrogen delivery for drug-free radiation enteritis therapy

Abstract excerpt

<title>Abstract</title> <p>Radiation enteritis affects over 90% of patients undergoing pelvic or abdominal radiotherapy, primarily due to radiation-induced production of reactive oxygen and nitrogen species (RONS). Active hydrogens possess broad-spectrum RONS scavenging ability, demonstrating great potential in radioprotection. However, owing to the intestinal mucus barrier and short lifespan of active hydrogens,...

Topics

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• Cancer-Associated Fibroblasts
• Cell Line, Tumor
• Disease Models, Animal
• Hydrogen
• Mice
• Mice, Inbred BALB C
• Nanoparticles
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

be2888c3-7431-54c9-a3c6-a29d254a3363

DOI

10.21203/rs.3.rs-5221636/v1