Article

<i>Mysm1</i> mutations in <i>meander tail</i> mice cause anterior-selective cerebellum malformation

2026-02-26

Abstract excerpt

Mouse meander tail ( mea ) mutations produce kinked tails and selective malformation of the cerebellum anterior compartment. The anterior cerebellum defects are cell autonomous with respect to granule cell precursors, but the molecular basis has not been known. Myb-like, SWIRM, and MPN domain containing protein 1 (MYSM1) is a chromatin-associated deubiquitinase that promotes gene expression by removing monoubiqu...

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Literature Corpus work: 51014469-e72a-5900-8553-a7122921049c
DOI: 10.64898/2026.02.25.708017

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