Article

Circadian disruption does not alter tumorigenesis in a mouse model of lymphoma

2023-09-28

Abstract excerpt

<h4>Background: </h4> Disruption of natural light cycles, as experienced by shift workers, is linked to enhanced cancer incidence. Several mouse models of cancer develop more severe disease when exposed to irregular light/dark cycles, supporting the connection between circadian disruption and increased cancer risk. Cryptochrome 2 (CRY2), a repressive component of the molecular circadian clock, facilitates turnover...

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Literature Corpus work: 50b92580-8094-5a96-82e7-ff282aa65d67
DOI: 10.12688/f1000research.125272.2

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