Article
Clock-cancer connection in non-Hodgkin's lymphoma: a genetic association study and pathway analysis of the circadian gene cryptochrome 2.
Cancer research - 15 Apr 2009
Hoffman Aaron E, Zheng Tongzhang, Stevens Richard G, Ba Yue, Zhang Yawei, Leaderer Derek, Yi Chunhui, Holford Theodore R, Zhu Yong
Abstract excerpt
Circadian genes have the potential to influence a variety of cancer-related biological pathways, including immunoregulation, which may influence susceptibility to non-Hodgkin's lymphoma (NHL). However, few studies have examined the role of circadian genes in lymphomagenesis. The current study examined Cryptochrome 2 (CRY2), a core circadian gene and transcriptional repressor, as a potential circadian biomarker...
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