Article

Splicing dysregulation in glioblastoma alters the function of cell migration-related genes

2024-10-06

Abstract excerpt

<h4>Summary</h4> Glioblastoma (GBM) has a poor prognosis with a high recurrence and low survival rate. Previous RNA-seq analyses have revealed that alternative splicing (AS) plays a role in GBM progression. Here, we present a novel AS analysis method (Semi-Q) and describe its use to identify GBM-specific AS events. We analyzed RNA-seq data from normal brain (NB), normal human astrocytes (NHAs) and GBM samples, an...

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Literature Corpus work: 5089a69e-192f-5495-abff-4f07feaa5cdd
DOI: 10.1101/2024.10.05.616792

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