Article
Identification of Prognostic Signatures of Alternative Splicing in Glioma.
Journal of molecular neuroscience : MN - 1 Oct 2020
Zeng Yu, Zhang Peidong, Wang Xizhao, Wang Ke, Zhou Mingfeng, Long Hao, Lin Jie, Wu Zhiyong, Gao Liang, Song Ye
Abstract excerpt
Alternative splicing (AS) is a ubiquitous mechanism in which pre-mRNA can be spliced into divergent variants and involved in carcinogenesis and progression in several cancers. In the present study, we systematically profiled prognostic AS signatures involving both low grade glioma (LGG) and glioblastoma (GBM) and investigated the association of AS signatures with tumor grade and IDH1 status in glioma. Percent...
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