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Survival-Associated Differentially Expressed Alternative Splicing Signatures Reveal Neuron Signaling and Metabolism-Related Processes in Glioblastoma

2021-04-07

Abstract excerpt

<h4>Background: </h4> Alternative splicing (AS) is a molecular event that drives protein diversity by generating multiple mRNA isoforms. Increasing evidence shows that the differential expression of AS is related to tumorigenesis. However, a synthetic analysis for identifying the AS biomarkers attributed to glioblastoma (GBM) is mostly unexplored. MethodsAS percent-splice-in (PSI) data were obtained from the TCGA...

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Literature Corpus work
81cf59ee-c566-570b-a1e3-d512c11524aa
DOI
10.21203/rs.3.rs-375966/v1
Open publication

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Survival-Associated Differentially Expressed Alternative Splicing Signatures Reveal Neuron Signaling and Metabolism-Related Processes in GlioblastomaDOI 10.21203/rs.3.rs-375966/v1
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