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Article

The prognostic effects of somatic mutations in ER-positive breast cancer

2017-12-19

Abstract excerpt

More than 50 genes are recurrently affected by somatic mutation in estrogen receptor positive (ER+) breast cancer but prognostic effects have not been definitively established. Primary tumor DNA was therefore subjected to targeted sequencing from 625 postmenopausal (UBC-TAM series) and 328 premenopausal (MA12 trial) hormone receptor-positive (HR+) patients. Independent validation of prognostic interactions was ach...

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Identifiers and source

Literature Corpus work
5042a187-1ddb-568b-aa7f-d75e080b4632
DOI
10.1101/235846
Open publication

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The prognostic effects of somatic mutations in ER-positive breast cancerDOI 10.1101/235846
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