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Article

Induction of PIK3CA alterations during neoadjuvant letrozole may improve outcome in postmenopausal breast cancer patients.

Breast cancer research and treatment - 1 Nov 2020

Skriver Signe Korsgaard, Jensen Maj-Britt, Eriksen Jens-Ole, Ahlborn Lise Barlebo, Knoop Ann Soegaard, Rossing Maria, Ejlertsen Bent, Laenkholm Anne-Vibeke

Abstract excerpt

PURPOSE: Estrogen receptor positive (ER+) breast cancer constitutes almost 85% of all breast cancer patients and are a genetically highly heterogenic group. Data on the association of somatic alterations to outcome and prognosis are however sparse. In this neoadjuvant endocrine phase II trial including postmenopausal breast cancer patients with ER+, HER2 normal breast cancer, we investigated the rate of...

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PMID: 32748297
DOI: 10.1007/s10549-020-05833-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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