Article

Mesenchymal stem cells polarize macrophages to an anti-inflammatory phenotype to ameliorate diabetic nephropathy

2022-08-23

Abstract excerpt

<title>Abstract</title> <p>Background Diabetic nephropathy is closely related to immune-regulation, in which macrophages play a crucial role. In diabetic nephropathy, the classically activated macrophages (M1) increased while the alternatively activated macrophages (M2) decreased in kidney. Mesenchymal stem cells (MSCs) administration can alleviate diabetic nephropathy, however, the mechanisms still remain uncle...

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Literature Corpus work: 502fdf6f-fbd3-59eb-a93b-69e13463c850
DOI: 10.21203/rs.3.rs-1965742/v1

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