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Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic rats

2022-03-17

Abstract excerpt

<title>Abstract</title> <p>Background Mesenchymal stem cells (MSCs) exert anti-diabetic effects and improve long-term complications via secretory effects that regulate macrophage polarisation and attenuate inflammation. Enhancing the efficacy of MSCs needs to be explored further. The in vitro culture microenvironment influences the secretory profile of MSCs. Therefore, we hypothesised that a diabetic microenviro...

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Literature Corpus work
a600b233-e765-5823-a3c2-849b6c1551ad
DOI
10.21203/rs.3.rs-1436385/v1
Open publication

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Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic ratsDOI 10.21203/rs.3.rs-1436385/v1
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