Article

Human Umbilical Cord Mesenchymal stem cells Promote Uterine Scar Repair Through Regulating Macrophage Polarization

2022-04-21

Abstract excerpt

<h4>Background: </h4> Mesenchymal stem cells (Mesenchymal Stem Cells, MSCs) treatment can reduce inflammation during uterine scar repair. However, the exact mechanisms remain unclear. Methods A rat model of uterine injury was surgically established, and 5×10 5 hUC-MSCs were transplanted to each side of the uterus immediately after surgery. On days 14 and 30 following transplantation, uterine injury recovery were...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7d10331b-59ff-5151-924c-7f9ef2b67dca
DOI: 10.21203/rs.3.rs-1580224/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human Umbilical Cord Mesenchymal stem cells Promote Uterine Scar Repair Through Regulating Macrophage PolarizationDOI 10.21203/rs.3.rs-1580224/v1Read

Mesenchymal Stromal Cells Affect Disease Outcomes via Macrophage PolarizationSemantic proximity Read

Macrophages are involved in the protective role of human umbilical cord-derived stromal cells in renal ischemia-reperfusion injury.Semantic proximity Read

Transplantation of human umbilical cord mesenchymal stem cells promotes repair of uterine scars in rats through promoting angiogenesisSemantic proximity Read

Transplantation of human umbilical cord mesenchymal stem cells induces angiogenesis and promotes repair of uterine scars in ratsSemantic proximity Read

Mesenchymal stem cells polarize macrophages to an anti-inflammatory phenotype to ameliorate diabetic nephropathySemantic proximity Read

Umbilical cord-derived mesenchymal stem cells preferentially modulate macrophages to alleviate pulmonary fibrosisSemantic proximity Read

Mesenchymal stromal cells attenuate pulmonary fibrosis via macrophageSemantic proximity Read

Human embryonic stem cell-derived immunity-and-matrix-regulatory cells promote endometrial repair and fertility restoration in IUA ratsSemantic proximity Read

STAT6 up-regulation amplifies M2 macrophage anti-inflammatory capacity through mesenchymal stem cells.Semantic proximity Read

Human amnion favours tissue repair by inducing the M1-to-M2 switch and enhancing M2 macrophage features.Semantic proximity Read

Human umbilical cord mesenchymal stem cells derived Exosomes attenuate injury of myocardial infarction by miR-24-3p-promoted M2 macrophage polarizationSemantic proximity Read

Overexpression of HNF4α enhances umbilical cord mesenchymal stem cell function to treat acute liver failure in mice through macrophage polarizationSemantic proximity Read