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MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against renal injury in diabetic nephropathy through facilitating M2 macrophage polarization by targeting TRAF6

2021-09-08

Abstract excerpt

<title>Abstract</title> <p>Background Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a common cause of end-stage renal disease, but has no approved pharmacotherapy. Mesenchymal stem cells (MSCs) possess potent anti-inflammatory and immunomodulatory properties, which render them an attractive therapeutic tool for tissue damage and inflammation. Methods This study was designed to dete...

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Literature Corpus work
89c0ef84-9a85-503a-89a2-ca7f9b8cc839
DOI
10.21203/rs.3.rs-871704/v1
Open publication

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MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against renal injury in diabetic nephropathy through facilitating M2 macrophage polarization by targeting TRAF6DOI 10.21203/rs.3.rs-871704/v1
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