Article
Microfluidics-Enabled Digital Isothermal Cas13a Assay
2021-08-24
Abstract excerpt
The isothermal molecular diagnosis with CRISPR has attracted particular interest for the sensitive, specific detection of nucleic acids. However, most of the assays with Cas enzymes were performed in bulk assays using multistep approaches and hard to realize quantitative detection. Herein, we report Microfluidics-Enabled Digital Isothermal Cas13a Assay (MEDICA), a digital format of SHERLOCK with enhanced robustnes...
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Identifiers and source
- Literature Corpus work
- 50178643-63e1-5072-b593-9068b7777a31
- DOI
- 10.1101/2021.08.18.21262201
