Article

Sensitive and multiplexed RNA detection with Cas13 droplets and kinetic barcoding

2021-08-05

Abstract excerpt

<h4>SUMMARY</h4> Rapid and sensitive quantification of RNA is critical for detecting infectious diseases and identifying disease biomarkers. Recent direct detection assays based on CRISPR-Cas13a 1–4 avoid reverse transcription and DNA amplification required of gold-standard PCR assays 5 , but these assays have not yet achieved the sensitivity of PCR and are not easily multiplexed to detect multiple viruses or vari...

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Literature Corpus work: af621f83-58cf-52fa-bed2-d36c69786c47
DOI: 10.1101/2021.08.02.21261509

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