Article

Fat body-specific reduction of CTPS alleviates HFD-induced obesity

2022-05-13

Abstract excerpt

<h4>ABSTRACT</h4> High fat diet (HFD)-induced obesity is a multi-factorial disease including genetic, physiological, behavioral, and environmental components. Drosophila has emerged as a useful model of metabolic diseases. Cytidine 5′-triphosphate synthase (CTPS) is a key enzyme for the de novo synthesis of CTP, governing cellular level of CTP and phospholipid synthesis. We have demonstrated that CTPS show the...

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Literature Corpus work: 500e533f-7c13-507d-aac0-a6b0f685a4f2
DOI: 10.1101/2022.05.12.491743

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