Article
Only one isoform of Drosophila melanogaster CTP synthase forms the cytoophidium.
PLoS genetics - 1 Jan 2013
Azzam Ghows, Liu Ji-Long
Abstract excerpt
CTP synthase is an essential enzyme that plays a key role in energy metabolism. Several independent studies have demonstrated that CTP synthase can form an evolutionarily conserved subcellular structure termed cytoophidium. In budding yeast, there are two isoforms of CTP synthase and both isoforms localize in cytoophidium. However, little is known about the distribution of CTP synthase isoforms in Drosophila...
Topics
- Amino Acid Sequence
- Animals
- Carbon-Nitrogen Ligases
- Cell Nucleus
- Cytidine Triphosphate
- Cytoplasm
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Germ Cells
- Mutation
- Organelles
- Protein Isoforms