Article
The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer.
Oncotarget - 12 Jul 2016
Di Benedetto Anna, Mottolese Marcella, Sperati Francesca, Ercolani Cristiana, Di Lauro Luigi, Pizzuti Laura, Vici Patrizia, Terrenato Irene, Sperduti Isabella, Shaaban Abeer M, Sundara-Rajan Sreekumar, Barba Maddalena, Speirs Valerie, De Maria Ruggero, Maugeri-Saccà Marcello
Abstract excerpt
Male breast cancer (MBC) is a rare disease and its biology is poorly understood. Deregulated Hippo pathway promotes oncogenic functions in female breast cancer. We herein investigated the expression of the Hippo transducers TAZ/YAP and their target CTGF in MBC. Tissue microarrays containing samples from 255 MBC patients were immunostained for TAZ, YAP and CTGF. One hundred and twenty-nine patients were considered...
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