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Simultaneous screening of overexpressed genes in breast cancer for oncogenic drivers and tumor dependencies

9 Jun 2024

Abstract excerpt

There are hundreds of genes typically overexpressed in breast cancer cells and it's often assumed that their overexpression contributes to cancer progression. However, the precise proportion of these overexpressed genes contributing to tumorigenicity remains unclear. To address this gap, we undertook a comprehensive screening of a diverse set of seventy-two genes overexpressed in breast cancer. This systematic...

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PMID: 38851782
DOI: 10.1038/s41598-024-64297-w

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