Article

The HSV-1 immediate early protein ICP22 interacts with the human antisense function 1 protein to promote viral replication

2026-06-25

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is a common human pathogen that undergoes lytic replication in epithelial and other permissive cell types and can establish latency in peripheral neurons. ICP22 is a multifunctional HSV-1 immediate-early protein that localizes to the nucleus of infected cells; however, its interactions with host cellular factors remain incompletely understood. Here, ICP22 was demonstrated to int...

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Literature Corpus work: 4f738dd3-5a48-52be-a431-80c775849fc8
DOI: 10.64898/2026.06.24.734377

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