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Supercharged NK cells, unlike primary activated NK cells, effectively target ovarian cancer cells irrespective of MHC-class I expression

2023-09-22

Abstract excerpt

<title>Abstract</title> <p>Ovarian cancers are the fifth leading cause of cancer-related death among women in the United States. Significant decreases in the numbers and function of NK-cells in patients, as shown in this paper may significantly contribute to the survival and expansion of aggressive poorly-differentiated-cancer-stem-like-cells (PDCSCs) with no/low expression of MHC-class I. Indeed, when gene set e...

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Literature Corpus work
4f73345b-8679-5ea4-9fad-66ef3614be9d
DOI
10.21203/rs.3.rs-3328625/v1
Open publication

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Supercharged NK cells, unlike primary activated NK cells, effectively target ovarian cancer cells irrespective of MHC-class I expressionDOI 10.21203/rs.3.rs-3328625/v1
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