Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy

30 Aug 2024

Abstract excerpt

Dual-attribute immune cells possess advantageous features of cytotoxic T cells and natural killer (NK) cells and hold promise for advancing immunotherapy. Dual-attribute cell types such as invariant natural killer T cells, induced T-to-NK cells, and cytokine-induced killer cells have demonstrated efficacy and safety in preclinical and clinical studies. However, their limited availability hinders their widespread...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to CRISPR and Genetic Engineering
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39216483
DOI: 10.1016/j.crmeth.2024.100843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapyPMID 39216483Read ↗

Pluripotent stem cell-derived siTNK cells attack tumors via a synthetic CD8-CD28-TCR complexSemantic proximity Read ↗

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapySemantic proximity Read ↗

Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers.Semantic proximity Read ↗

Comparative analysis of iPSC-derived NK cells from two differentiation strategies reveals distinct signatures and cytotoxic activitiesSemantic proximity Read ↗

An Alternative Cell Therapy for Cancers: Induced Pluripotent Stem Cell (iPSC)-Derived Natural Killer CellsSemantic proximity Read ↗

Engineered iPSC ‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapySemantic proximity Read ↗

Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy.Semantic proximity Read ↗

Multiplexed iPSC platform for advanced NK cell immunotherapiesSemantic proximity Read ↗

Supercharged NK Cells Are a Unique Population of Cells Based on Transcriptomic, Single-Cell RNAseq, Proteomic, and Functional Characteristics; Comparison with Other NK Cell SubpopulationsSemantic proximity Read ↗

iPSC-Derived Natural Killer Cells for Cancer ImmunotherapySemantic proximity Read ↗

From induced pluripotent stem cell (iPSC) to universal immune cells: literature review of advances in a new generation of tumor therapiesSemantic proximity Read ↗

Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.