Article

Transcription Factor Gene <i>Pea3</i> Regulates Erectile Function in Mice

2021-11-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Male mice with homozygous loss of function mutations of the ETS transcription factor gene Pea3 ( Pea3 null) are infertile due to their inability to deposit semen plugs, however the specific deficits in male sexual behaviors that drive this phenotype are unknown. <h4>Aim</h4> To investigate the regulatory role of the Pea3 gene in organizing gross sexual behaviors and er...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4f6df21a-0ef6-581e-b8f8-b6da7d566d25
DOI: 10.1101/2021.11.15.468751

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcription Factor Gene <i>Pea3</i> Regulates Erectile Function in MiceDOI 10.1101/2021.11.15.468751Read

Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene.Semantic proximity Read

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity†Semantic proximity Read

The paternally expressed gene Peg3 regulates sexual experience-dependent preferences for estrous odors.Semantic proximity Read

Female genetic variation controlling timing of mating plug ejection in <i>Drosophila melanogaster</i>Semantic proximity Read

AKAP3-mediated type I PKA signaling is required for mouse sperm hyperactivation and fertilitySemantic proximity Read

Human <i>HPSE2</i> gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndromeSemantic proximity Read

Cooperation-based sperm clusters mediate sperm oviduct entry and fertilizationSemantic proximity Read

Sexual behaviour in a murine model of Mucopolysaccharidosis type I (MPS I)Semantic proximity Read

In vivo three-dimensional tracking of sperm behaviors in the mouse oviductSemantic proximity Read

Reduction of Spermatogenesis but Not Fertility in Creb3l4-Deficient MiceSemantic proximity Read

Ejaculated Mouse Sperm Enter Cumulus-Oocyte Complexes More Efficiently In Vitro than Epididymal SpermSemantic proximity Read

Sexual behaviour in a murine model of mucopolysaccharidosis type I (MPS I).Semantic proximity Read